《英文msh詞典》Glycoprotein Ib beta
[入口詞] Glycoprotein Ib beta
[主題詞] Platelet Glycoprotein GPIb-IX Complex
[英文釋義] Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides,GPIb alpha,GPIb beta,and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.